Increasing Awareness of Disparities in Cardiovascular Health Care

It is well established that cardiovascular disease is disproportionately higher in blacks than in whites, Asians and Hispanics.  In fact, death from heart disease is 1.7 to 2-fold higher in black men compared to white men 45 years and older.  Similarly in women, cardiovascular events are also elevated in blacks compared to whites with an approximate 2.5-fold risk beginning in middle-age (45+ years).

According to the American Heart Association, 7 core health behaviors/risk factors shape the likelihood of developing a heart attack or stroke. They include: blood pressure (BP), body mass index (BMI), cholesterol level, dietary habits, glucose control, physical activity and smoking history.  In an otherwise healthy individual, “ideal” cardiovascular health would be defined as optimal core health behaviors/risk factors such as 1) BP less than 120/70; 2) BMI between 18-24.9 kg/m², 3) LDL cholesterol levels less than 100 mg/dL, 4) a diet low in animal based saturated and trans fats, 5) fasting blood glucose less than 100 mg/dL, 6) being physically active (at least 150 minutes of mild-moderate activity [such as brisk walking at 3-5 mph] per week) and 7) not smoking cigarettes.  Unfortunately, less than 1 in 3 adult men/women exhibit ideal cardiovascular health led by Asians (29%) and Whites (19%) while Hispanics and Blacks (14% and 10%) lag well. behind this milestone.   For a more comprehensive review on this topic, check out our recent paper led by my colleague, Dr. Penny-Kris Etherton.

Listed below are further insights into the barriers, challenges and opportunities for implementing change to reduce disparities in diet-related heart disease based upon the publication in the Journal of the American Heart Association.

1. Food deserts are areas that lack access to affordable foods that comprise a healthy diet (e.g., fruits, vegetables, low‐fat milk, whole grains). In Baltimore, high availability of healthy foods was only present in 19% of predominately black neighborhoods compared to 68% of white neighborhoods.
2. A study conducted in Atlanta found that individuals in food deserts were more likely to be black, less likely to be college graduates, and had lower income compared with individuals in nonfood deserts.
3. Access to supermarkets stocking affordable healthy foods is associated with greater likelihood of fulfilling healthy dietary recommendations. For each supermarket present in a census tract, the intake of fruits and vegetables rose by 32%.
4. Large disparities exist in supermarket access in predominately black communities. There are 5 times more supermarkets in census tracts where whites live compared to where blacks reside.
5. Approximately 3.5% of the US population live in a food swamp, defined by the ratio of fast-food outlets and convenience stores to supermarkets and grocery stores in a given area.
6. Financial incentives to encourage purchasing of healthy foods and/or disincentives or restrictions on purchasing of unhealthy foods improves diet quality, especially in low‐income groups. A 10% reduction in the price of healthy foods increased consumption by 12%.
7. An increase in the cost (tax) of unhealthy foods decreased consumption by 6%. This approach reduced intake of sugar‐sweetened beverages (9%), fast food (3%), and other unhealthy beverages (5%).

Dr. Michael Miller is Professor of Cardiovascular Medicine at the University of Maryland School of Medicine in Baltimore, Maryland.  Check him out on twitter: @mmillermd1

Early Onset Hypertension= Early Onset Dementia

 

 

A new study out this week has found that being diagnosed with elevated blood pressure at a young age, is associated with risk of early dementia.

The study published in the American Heart Association journal, Hypertension analyzed 11,399 Chinese adults who were diagnosed with hypertension at 3 age groups: 1)when they were younger than age 35; 2) between ages 35 to 44 and 3) aged 45 to 54 years. Another 11,399 men and women without a history of high blood pressure served as the control group.  Brain MRI scans were performed in all participants. The results of the study indicated that in all 3 comparator age groups, those with hypertension exhibited smaller brain (volume) sizes with the largest difference observed in the group under age 35.

Among the subjects who developed any type of dementia during the study period, the risk was 61% higher in men and women 35-44 years of age who had been diagnosed with hypertension compared to similar aged normotensive controls. In addition, vascular dementia was increased 45-69% when hypertension was diagnosed between ages 35-54 years. To review this paper, click here.

The study supports early identification and treatment of high blood pressure – it stands to reason that control of hypertension at a young age would reduce development of dementia.

High blood pressure can occur under a variety of circumstances and may be associated with the following:

1. Exercise induced hypertension (systolic pressure greater than 210 mmHg in men and 190 mmHg in women with exercise) is associated with a 35-40% increased risk of cardiovascular events and mortality.
2. Hypertension of the eyes (ocular hypertension) raises the risk of glaucoma.  Risk factors for ocular hypertension include diabetes, hypertension, extreme nearsightedness and chronic steroid use.
3. Black licorice can raise blood pressure and cause palpitations when 2 or more ounces are consumed per day.
4. Herbal supplements that may raise blood pressure include ginseng, guarana, ma-huang and St. John’s Wort.
5. Examples of commonly used drugs that may raise blood pressure include NSAIDs (ibuprofen), steroids (prednisone), decongestants (pseudoephedrine), antidepressants (fluoxetine) and anti-infectives (ketoconazole).
6. The 4 “classic H signs” of Pheochromocytoma, Hyperhydrosis (excessive sweating), Hypertension, Heart palpitations and Headache are only observed in 40% of cases.
7. Hypertension with disproportionate pulses (reduced in lower compared to upper extremities) could be due to narrowing of the aorta (coarctation). Coarctation is associated with exercise induced hypertension.
8. Recent onset of high blood pressure associated with kidney stones, bone pain and abdominal pain (also known as “stones, bones and groans”) may be the result of high calcium levels due to an overactive parathyroid gland.
9. Hypertension is observed in up to 70% of those affected with obstructive sleep apnea. Treatment of sleep apnea and its underlying causes, may effectively reduce blood pressure.
10. Up to 30% of patients with hypertension do not respond effectively to 3 blood pressure medications. The most common condition associated with “resistant hypertension” is obstructive sleep apnea.
11. A recently diagnosed elevation in blood pressure that exceeds 150/100 mmHg on 3 different days should be screened for the rare medical condition, primary aldosteronism (Conn’s Syndrome).
12. A young woman with recent onset hypertension in association with tinnitus (ringing in the ears), dizziness, neck pain and poor kidney function may be due to another rare medical condition, fibromuscular dysplasia, recently been linked to spontaneous coronary artery dissection (SCAD).
13. Consider a workup for acromegaly in someone who has recently developed hypertension along with an increase in shoe (and glove) size. Complications of acromegaly include resistant hypertension, diabetes, and an enlarged heart, thereby raising  the risk of arrhythmia (abnormal heart rhythm) and sudden death.

Dr. Michael Miller is Professor of Cardiovascular Medicine at the University of Maryland School of Medicine in Baltimore, Maryland.  Check him out on twitter: @mmillermd1